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Studied drug
|
Proposed method
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Comparison method [11]
|
|---|
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Amount taken (ng/mL)
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Amount found (ng/mL)
|
% Found
|
% Found
|
|---|
|
Column (A)
|
Column (B)
|
Column (A)
|
Column (B)
|
Column (A)
|
Column (B)
|
|---|
|
Epclusa® tablet (SFV 400 mg/VPS100 mg)
|
1.0
|
2.5
|
0.982
|
2.449
|
98.20
|
97.99
|
102.45
|
|
3.0
|
5.0
|
2.995
|
4.827
|
99.84
|
96.53
|
101.78
|
|
5.0
|
10.0
|
5.049
|
9.782
|
100.97
|
97.82
|
98.91
|
|
Mean
| | | | |
99.67
|
97.45
|
101.05
|
|
±SD
| | | | |
1.39
|
0.80
|
1.88
|
|
t-test
| | | | |
2.74
|
3.05
|
(2.78)*
|
|
F-test
| | | | |
1.82
|
5.55
|
(19.0)*
|
- Each result is the average of three separate determinations
- * The figures between parentheses are the tabulated t and F values at P = 0.05 [17]
